Dupixent® (dupilumab) is a prescription injection manufactured by Sanofi and Regeneron and first approved by the FDA in 2017. It is commonly prescribed for patients of all ages — including children as young as six months old — with moderate-to-severe eczema (atopic dermatitis), asthma, chronic sinusitis with nasal polyps, and eosinophilic esophagitis. For many people, it provided relief where other medications had failed.
In recent years, however, Dupixent® has been linked to cutaneous T-cell lymphoma (CTCL), a rare and serious form of non-Hodgkin lymphoma. Studies published in 2024 and 2025 suggest that Dupixent® patients may face a 300% higher risk of developing CTCL yet manufacturers never warned healthcare providers or patients about this risk.
Cutaneous T-cell lymphoma is a rare cancer of the immune system that begins in the skin. At first, it can look almost the same as eczema, with red or scaly patches. Over time, it may turn into thicker lesions or tumors, and in advanced stages it can spread to lymph nodes and internal organs.
Because CTCL often begins with skin symptoms that closely resemble eczema or psoriasis, it is often misdiagnosed. Tragically, this also means that some patients diagnosed with eczema may have had undetected CTCL when they started Dupixent®. In those cases, the drug may have hidden the cancer’s early signs or delayed a proper diagnosis.
Patients and families across the country are pursuing legal claims against manufacturers Sanofi and Regeneron. These lawsuits allege that:
Drug manufacturers are being held accountable for their failure to warn patients about the harm that their drugs could cause.
Patients who have taken Dupixent® and later been diagnosed with cutaneous T-cell lymphoma should take the following steps:
Taking action promptly can help protect your ability to seek compensation and hold drug manufacturers accountable.
Dupixent® cases are now underway. Individual lawsuits have now been filed, and we expect the number of cases to rise significantly as patients and their families learn about the connection between Dupixent® and cancer.
At Morris James, our attorneys are currently investigating emerging Dupixent® claims in multiple states. We are here to help families hurt by negligent drug manufacturers and advise them about their legal options.
A diagnosis of cutaneous T-cell lymphoma can be devastating. Treatment may involve radiation, chemotherapy, immunotherapy, or stem cell transplants. Even when managed, the disease can recur or progress, requiring expensive medical interventions, lifelong care, and exhausting vigilance.
For families, the burden extends beyond medical treatment. Patients may be unable to work or may face reduced earning capacity. Out-of-pocket medical expenses can accumulate quickly. The emotional toll of coping with a cancer diagnosis, while also questioning whether it could have been prevented with better warnings, can be overwhelming.
Lawsuits are one way for patients and families to pursue accountability and financial recovery for these burdens.
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